Article
Interactions Between Polygenic Pleiotropy and Air Pollution in the Pathogenesis of Atopic Dermatitis.
Dermatitis : contact, atopic, occupational, drug - 1 Jan 2026
Chen Yun-Wen, Chen I-Chieh, Yang Hui-Wen, Tang Kuo-Tung, Chen Hsin-Hua, Huang Wen-Nan, Chen Yi-Hsing, Chen Yi-Ming
Abstract excerpt
Background: The polygenic risk score (PRS) for atopic dermatitis (AD) shows promise for early intervention. In addition, air pollution has been linked to AD.Objective: This study aims to investigate the combined effects of PRS and air pollutants on the onset of AD in the Asian population.Methods: This case-control study recruited AD patients from Taiwan Precision Medicine Initiative. Logistic regression analyzed...
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