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Article

Generalisability of ARDS biological subphenotype models in Asians: an international, multicentre, prospective biomarker study.

Thorax - 16 Feb 2026

Yang Haopu, Xia Jingen, Huang Xu, Bai Yu, Jin Dan, Nouraie Seyed Mehdi, McVerry Bryan J, Morris Alison, Kitsios Georgios D, Wang Chen, Zhan Qingyuan

Abstract excerpt

PURPOSE: Subphenotype classifiers for acute respiratory distress syndrome (ARDS) dichotomise patients into hyperinflammatory versus hypoinflammatory subgroups. These models demonstrated prognostic and predictive values but were developed primarily in Caucasian populations. Generalisability of these models in Asian patients, who experience worse clinical outcomes, has not been established. We aimed to profile host...

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PMID: 41167619
DOI: 10.1136/thorax-2025-223421

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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