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Article

T-cell immunoglobulin- and mucin-domain-containing molecule 3 gene polymorphisms and prognosis of non-small-cell lung cancer.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Apr 2013

Bai Jianwen, Li Xiaoyan, Tong Danian, Shi Weiwei, Song Haihan, Li Qinchuan

Abstract excerpt

Lung cancer is the leading cause of death worldwide. Non-small-cell lung cancer (NSCLC) accounts for most of these cases. T-cell immunoglobulin- and mucin-domain-containing molecule 3 (TIM-3) has been established as a negative regulatory molecule and plays a critical role in immune tolerance. Studies have shown that polymorphisms in TIM-3 gene can be associated with various diseases. The aim of this study was to...

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PMID: 23359271
DOI: 10.1007/s13277-012-0610-1

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