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Article

Clonal Hematopoiesis of Indeterminate Potential After Radiation Therapy.

International journal of radiation oncology, biology, physics - 15 Mar 2026

Crants Shelby A, Olson Sydney S, Li Yajing, Bejan Cosmin A, Vlasschaert Caitlyn, Mack Taralynn M, Pershad Yash, Kishtagari Ashwin, Reed Sarah C, Croessmann Sarah, Roden Dan M, Osterman Travis J, Shinohara Eric T, Bick Alexander G, Park Ben H, Luo Leo Y

Abstract excerpt

PURPOSE: Clonal hematopoiesis of indeterminate potential (CHIP) is a condition associated with increased risk of hematologic malignancies and cardiovascular diseases. Although radiation therapy has been identified as a risk factor for CHIP, specific radiation factors that influence the development of CHIP remain unclear. METHODS AND MATERIALS: We identified 489 patients with cancer who underwent radiation therapy...

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Identifiers

PMID: 41138783
DOI: 10.1016/j.ijrobp.2025.10.006
PMCID: PMC13339994

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