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Article

Clinically Actionable Hypertrophic Cardiomyopathy Genes in South Asian Indian Patients.

Journal of the American Heart Association - 4 Nov 2025

Rao Vinay J, Sairam Thiagarajan, Rathinavel Andiappan, Mohanan Kurukkanparampil Sreedharan, Ahamed Hisham, Shenthar Jayaprakash, Dhandapany Perundurai S

Abstract excerpt

BACKGROUND: Primary hypertrophic cardiomyopathy (HCM) is predominantly a genetic disease causing left ventricular hypertrophy in the absence of other cardiac and systemic metabolic diseases. Currently, limited data exist on the prevalence of clinically actionable gene variants for primary HCM in South Asian Indian (SAI) patients, which are necessary for minimizing disparities in interpreting ancestry-specific...

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Source

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Identifiers

PMID: 41128141
DOI: 10.1161/JAHA.125.042036
PMCID: PMC12684790

Genes

MYH6
MYBPC3
MYH7

Provenance

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