Article

Influence of ethnicity and consanguinity on the genetic architecture of Hypertrophic Cardiomyopathy: insights from an understudied population

2022-10-10

Abstract excerpt

Hypertrophic cardiomyopathy (HCM) is an inherited cardiac condition characterized by phenotypic heterogeneity that could partly be explained by the variability in genetic variants contributing to disease. Accurate interpretation of these variants constitutes a major challenge for diagnosis and implementing precision medicine, especially in understudied populations. Here, we leverage ancestry-matched Egyptian patie...

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Literature Corpus work: 1212c778-4e20-5f00-a431-d757716df8fa
DOI: 10.1101/2022.10.09.22280408

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