Article
Causative Variants for Inherited Cardiac Conditions in a Southeast Asian Population Cohort.
Circulation. Genomic and precision medicine - 1 Apr 2022
Tomar Swati, Klinzing David C, Chen Ching Kit, Gan Louis Hanqiang, Moscarello Tia, Reuter Chloe, Ashley Euan A, Foo Roger
Abstract excerpt
BACKGROUND: Variable penetrance and late-onset phenotypes are key challenges for classifying causal as well as incidental findings in inherited cardiac conditions. Allele frequencies of variants in ancestry-specific populations, along with clinical variant analysis and interpretation, are critical to determine their true significance. METHODS: Here, we carefully reviewed and classified variants in genes...
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