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Article

Ethnicity, consanguinity, and genetic architecture of hypertrophic cardiomyopathy.

European heart journal - 21 Dec 2023

Allouba Mona, Walsh Roddy, Afify Alaa, Hosny Mohammed, Halawa Sarah, Galal Aya, Fathy Mariam, Theotokis Pantazis I, Boraey Ahmed, Ellithy Amany, Buchan Rachel, Govind Risha, Whiffin Nicola, Anwer Shehab, ElGuindy Ahmed, Ware James S, Barton Paul J R, Yacoub Magdi, Aguib Yasmine

Abstract excerpt

AIMS: Hypertrophic cardiomyopathy (HCM) is characterized by phenotypic heterogeneity that is partly explained by the diversity of genetic variants contributing to disease. Accurate interpretation of these variants constitutes a major challenge for diagnosis and implementing precision medicine, especially in understudied populations. The aim is to define the genetic architecture of HCM in North African cohorts...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 37431535
DOI: 10.1093/eurheartj/ehad372
PMCID: PMC10733735

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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