Article
Null mutation of the p67phox subunit of NOX2 permits compensatory changes in renal blood flow during the development of salt-sensitive hypertension in SS rats.
American journal of physiology. Renal physiology - 1 Nov 2025
Evans Louise C, Dayton Alex, Kurth Terry, Anidu Babatunde S, Polichnowski Aaron J, Cowley Allen W
Abstract excerpt
In the current study, we used SSp67phox-/- to assess the involvement of oxidative stress in the regulation of renal blood flow during the development of salt-sensitive hypertension in Dahl salt-sensitive (SS) rats. We performed continuous assessment of mean arterial blood pressure (MAP) and renal blood flow (RBF) over a 2-wk period using radiotelemetry and ultrasound flow probes, respectively. In initial time...
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