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Preclinical Positron Emission Tomography Imaging of B7–H3 Expression Using Affibody Molecules Labeled with Gallium-68

4 Sept 2025

Abstract excerpt

High Resolution Image Download MS PowerPoint Slide Affibody molecules, nonimmunoglobulin scaffold proteins, have a high potential as probes for molecular imaging of different molecular targets. One of the molecular targets for radionuclide diagnosis and therapy is B7–H3 (known as CD276), which is overexpressed in various cancers, whereas its expression is low in most normal organs and tissues. The visualization...

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PMID: 41098568
DOI: 10.1021/acsptsci.5c00320

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