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68Ga-Labeled Glycopeptides as Effective Tools for Liver Function Imaging

17 Feb 2025

Abstract excerpt

High Resolution Image Download MS PowerPoint Slide [ 99m Tc]Tc-GSA, an albumin-based glycoprotein, is routinely used in Japan to measure the asialoglycoprotein receptor (ASGR) density via single photon emission tomography. Here we describe the development of 68 Ga-labeled peptide-based alternatives. Peptides were assembled on a solid support using a fragment coupling strategy. Glycosylation was carried out via a...

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Share to Glycosylation and Glycoproteins Research
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PMID: 39960224
DOI: 10.1021/acs.molpharmaceut.4c01453

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