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Article

Thyroid disorders and pregnancy loss: a bidirectional mendelian randomization exploration.

BMC pregnancy and childbirth - 14 Oct 2025

Chen Panyu, Zhao Weie, Li Yujie, Jia Lei, Fang Cong, Li Manchao

Abstract excerpt

OBJECTIVE: Thyroid hormones are essential for normal pregnancy and fetal development. The relationship between thyroid disease and the risk of spontaneous abortion (SA) and recurrent spontaneous abortion (RSA) has been reported, but causality is unclear. The purpose of this study was to investigate whether there is a causal association between thyroid disorders and SA/RSA. METHODS: In this bidirectional mendelian...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 41088040
DOI: 10.1186/s12884-025-08146-2
PMCID: PMC12522347

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