Article
Causal relationship between thyroid dysfunction and ovarian cancer: a two-sample Mendelian randomization study.
BMC cancer - 23 May 2024
Wang Tingting, Wang Xiaoqin, Wu Jun, Li Xin
Abstract excerpt
PURPOSE: Observational studies and clinical validation have suggested a link between thyroid dysfunction and an elevated ovarian cancer (OC) risk. However, whether this association indicates a cause-and-effect relationship remains uncertain. We aimed to investigate the plausible causal impact of thyroid dysfunction on OC through a Mendelian randomization (MR) study. METHODS: Genome-wide association study (GWAS)...
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