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Assessing the Genetic Integrity of Embryos Carrying X/Y-Autosome-Balanced Translocations through SNP-Based PGT-SR.

Cytogenetic and genome research - 1 Jan 2026

Lan Yueyun, Shu Jinhui, He Sheng, Luo Jingsi, Su Jiasun, Li Wei, Zhou Chaofan, Tang Xianglian, Wei Yuan, Huang Minpan, Wang Caizhu, Zhao Xin, Li Zhan, Qiu Qingming, Zhou Hong, Huang Peng

Abstract excerpt

INTRODUCTION: The influence of X/Y-autosomal translocations on reproductive competence is determined by both the cytogenetic positioning of translocation breakpoints and the potential disruption of critical genomic regions essential for reproductive physiology, particularly gene-dense Y-chromosomal segments or X-chromosome loci associated with ovarian folliculogenesis. This investigation examined 4 cases of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 41086126
DOI: 10.1159/000548936

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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