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Article

A comprehensive and universal approach for embryo testing in patients with different genetic disorders.

Clinical and translational medicine - 1 Jul 2021

Zhang Shuo, Lei Caixia, Wu Junping, Xiao Min, Zhou Jing, Zhu Saijuan, Fu Jing, Lu Daru, Sun Xiaoxi, Xu Congjian

Abstract excerpt

BACKGROUND: In vitro fertilization (IVF) with preimplantation genetic testing (PGT) has markedly improved clinical pregnancy outcomes for carriers of gene mutations or chromosomal structural rearrangements by the selection of embryos free of disease-causing genes and chromosome abnormalities. However, for detecting whole or segmental chromosome aneuploidies, gene variants or balanced chromosome rearrangements in...

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Identifiers

PMID: 34323405
DOI: 10.1002/ctm2.490
PMCID: PMC8265165

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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