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Article

The establishment and application of preimplantation genetic haplotyping in embryo diagnosis for reciprocal and Robertsonian translocation carriers.

BMC medical genomics - 17 Oct 2017

Zhang Shuo, Lei Caixia, Wu Junping, Zhou Jing, Sun Haiyan, Fu Jing, Sun Yijuan, Sun Xiaoxi, Lu Daru, Zhang Yueping

Abstract excerpt

BACKGROUND: Preimplantation genetic diagnosis (PGD) is now widely used to select embryos free of chromosomal copy number variations (CNV) from chromosome balanced translocation carriers. However, it remains a difficulty to distinguish in embryos between balanced and structurally normal chromosomes efficiently. METHODS: For this purpose, genome wide preimplantation genetic haplotyping (PGH) analysis was utilized...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 29041973
DOI: 10.1186/s12920-017-0294-x
PMCID: PMC5646120

Genes

PGD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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