Article
Single-nucleotide polymorphism microarray-based preimplantation genetic diagnosis is likely to improve the clinical outcome for translocation carriers.
Human reproduction (Oxford, England) - 1 Sept 2013
Tan Y-Q, Tan K, Zhang S-P, Gong F, Cheng D-H, Xiong B, Lu C-F, Tang X-C, Luo K-L, Lin G, Lu G-X
Abstract excerpt
STUDY QUESTION: Is preimplantation genetic diagnosis (PGD) for translocation carriers more effective when done with a single-nucleotide polymorphism (SNP) array using trophectoderm (TE) biopsy and frozen embryo transfer (FET) compared with traditional PGD based on fluorescence in situ hybridization (FISH-PGD) using blastomere biopsy and fresh embryo transfer? SUMMARY ANSWER: The procedure using the SNP array...
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