Back to search

Article

PGT-SR: A Comprehensive Overview and a Requiem for the Interchromosomal Effect

2023-03-06

Abstract excerpt

Preimplantation genetic testing for structural rearrangements (PGT-SR) was one of the first applications of PGT, with initial cases being worked up in the Delhanty lab. It is the least well-known of the various forms of PGT but nonetheless provides effective treatment for many carrier couples. Structural chromosomal rearrangements (SRs) lead to infertility, repeated implantation failure, pregnancy loss, and congen...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
cc59eded-b282-59a7-94f1-9030709530f5
DOI
10.3390/dna3010004
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
PGT-SR: A Comprehensive Overview and a Requiem for the Interchromosomal EffectDOI 10.3390/dna3010004
Interchromosomal effect in carriers of translocations and inversions assessed by preimplantation genetic testing for structural rearrangements (PGT-SR)Semantic proximity
Preimplantation Genetic Diagnosis—An OverviewSemantic proximity
Preimplantation Genetic Testing for Chromosomal Abnormalities: Aneuploidy, Mosaicism, and Structural RearrangementsSemantic proximity
Embryos of Robertsonian Translocation Carriers Exhibit a Mitotic Interchromosomal Effect That Enhances Genetic Instability during Early DevelopmentSemantic proximity
The impact of patient, embryo, and translocation characteristics on the ploidy status of young couples undergoing preimplantation genetic testing for structural rearrangements (PGT-SR) by next generation sequencing (NGS)Semantic proximity
Chromosomal analysis in IVF: just how useful is it?Semantic proximity
ESHRE PGT Consortium good practice recommendations for the detection of structural and numerical chromosomal aberrations†Semantic proximity
Evaluation of chromosomal abnormalities from preimplantation genetic testing to the reproductive outcomes: a comparison between three different structural rearrangements based on next-generation sequencingSemantic proximity
PGT for structural chromosomal rearrangements in 300 couples reveals specific risk factors but an interchromosomal effect is unlikelySemantic proximity
Successful pregnancy to a complex chromosome rearrangement carrier by next-generation cytogenetics and preimplantation genetic testingSemantic proximity
Multi-centre evaluation of a comprehensive preimplantation genetic test through haplotyping-by-sequencingSemantic proximity
Preimplantation genetic testing for complex chromosomal rearrangements: clinical outcomes and potential risk factorsSemantic proximity
Select a neighboring publication to make it the new centre.