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Awareness, knowledge, and attitudes toward polygenic risk scores for breast cancer in multiethnic high-risk cohorts of women.

Genetics in medicine : official journal of the American College of Medical Genetics - 1 Dec 2025

Freeman Jincong Q, Sun Yijia, Guo Wenji, Aschebrook-Kilfoy Briseis, Essling Cara, McEvilly Jan-Marie, Siljander Ilona, Basdag Hatice, Olopade Olufunmilayo I, Huo Dezheng

Abstract excerpt

PURPOSE: To examine awareness, knowledge, and attitudes toward breast cancer (BC) polygenic risk scores (PRS) in women with high risk. METHODS: We surveyed women without BC enrolled in the Chicago Multiethnic Epidemiologic BC Cohort and Cancer Prone Registry between July and September 2024. PRS awareness was defined as having ever read/heard about PRS and discussed PRS with a provider. PRS knowledge scores range...

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Identifiers

PMID: 41084865
DOI: 10.1016/j.gim.2025.101603
PMCID: PMC12574554

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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