Article
Uptake of polygenic risk information among women at increased risk of breast cancer.
Clinical genetics - 1 Mar 2020
Yanes Tatiane, Meiser Bettina, Kaur Rajneesh, Scheepers-Joynt Maatje, McInerny Simone, Taylor Shelby, Barlow-Stewart Kristine, Antill Yoland, Salmon Lucinda, Smyth Courtney, Young Mary-Anne, James Paul A
Abstract excerpt
Polygenic risk scores (PRSs) are increasingly being implemented to assess breast cancer risk. This study aimed to assess and determine factors associated with uptake of PRS among women at increased risk of breast cancer for whom genetic testing to date had been uninformative. Participants were recruited from the Variants in Practice study from which breast cancer PRS had been calculated. Four hundred women were...
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