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Article

Proteasome regulation of petite-negativity in fission yeast.

BMC biology - 9 Oct 2025

Amberg Katie Lin, Hao Lyrica, Cranz-Mileva Susanne, Zaratiegui Mikel

Abstract excerpt

BACKGROUND: Mitochondria carry out essential functions in eukaryotic cells. The mitochondrial genome encodes factors critical to support oxidative phosphorylation and mitochondrial protein import necessary for these functions. However, organisms like budding yeast can readily lose their mitochondrial genome, yielding respiration-deficient petite mutants. The fission yeast Schizosaccharomyces pombe is...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 41068765
DOI: 10.1186/s12915-025-02409-2
PMCID: PMC12512697

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