Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A hunt for OM45 synthetic petite interactions in Saccharomyces cerevisiae reveals a role for Miro GTPase Gem1p in cristae structure maintenance.

MicrobiologyOpen - 1 Oct 2021

Shvetsova Antonina, Masud Ali J, Schneider Laura, Bergmann Ulrich, Monteuuis Geoffray, Miinalainen Ilkka J, Hiltunen J Kalervo, Kastaniotis Alexander J

Abstract excerpt

Om45 is a major protein of the yeast's outer mitochondrial membrane under respiratory conditions. However, the cellular role of the protein has remained obscure. Previously, deletion mutant phenotypes have not been found, and clear amino acid sequence similarities that would allow inferring its functional role are not available. In this work, we describe synthetic petite mutants of GEM1 and UGO1 that depend on...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to DNA, Fungal
Share to DNA, Mitochondrial

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to GTP Phosphohydrolases

Share to Mitochondria

Share to Mitochondrial Membranes

Share to Mitochondrial Precursor Protein Import Complex Proteins

Share to Mitochondrial Proteins

Share to Saccharomyces cerevisiae Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 34713605
DOI: 10.1002/mbo3.1238
PMCID: PMC8501180

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A hunt for OM45 synthetic petite interactions in Saccharomyces cerevisiae reveals a role for Miro GTPase Gem1p in cristae structure maintenance.PMID 34713605Read ↗

Mmm1p, a mitochondrial outer membrane protein, is connected to mitochondrial DNA (mtDNA) nucleoids and required for mtDNA stability.Semantic proximity Read ↗

Cells lacking Pcp1p/Ugo2p, a rhomboid-like protease required for Mgm1p processing, lose mtDNA and mitochondrial structure in a Dnm1p-dependent manner, but remain competent for mitochondrial fusion.Semantic proximity Read ↗

A DRP-like pseudoenzyme coordinates with MICOS to promote cristae architectureSemantic proximity Read ↗

Proteasome regulation of petite-negativity in fission yeast.Semantic proximity Read ↗

Structure-function analysis of the yeast mitochondrial Rho GTPase, Gem1p: implications for mitochondrial inheritance.Semantic proximity Read ↗

PET genes of Saccharomyces cerevisiae.Semantic proximity Read ↗

A novel role of Mgm1p, a dynamin-related GTPase, in ATP synthase assembly and cristae formation/maintenance.Semantic proximity Read ↗

The petite mutation in yeasts: 50 years on.Semantic proximity Read ↗

The N-terminal intrinsically disordered domain of Mgm101p is localized to the mitochondrial nucleoid.Semantic proximity Read ↗

MMM1 encodes a mitochondrial outer membrane protein essential for establishing and maintaining the structure of yeast mitochondria.Semantic proximity Read ↗

A functional core of the mitochondrial genome maintenance protein Mgm101p in Saccharomyces cerevisiae determined with a temperature-conditional allele.Semantic proximity Read ↗

Human CCDC51 and yeast Mdm33 are functionally conserved mitochondrial inner membrane proteins that demarcate a subset of organelle fission eventsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.