Article
Multiple nutritional phenotypes of fission yeast mutants defective in genes encoding essential mitochondrial proteins.
Open biology - 1 Apr 2021
Uehara Lisa, Saitoh Shigeaki, Mori Ayaka, Sajiki Kenichi, Toyoda Yusuke, Masuda Fumie, Soejima Saeko, Tahara Yuria, Yanagida Mitsuhiro
Abstract excerpt
Mitochondria are essential for regulation of cellular respiration, energy production, small molecule metabolism, anti-oxidation and cell ageing, among other things. While the mitochondrial genome contains a small number of protein-coding genes, the great majority of mitochondrial proteins are encoded by chromosomal genes. In the fission yeast Schizosaccharomyces pombe, 770 proteins encoded by chromosomal genes...
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