Article
Multivariate genomic analysis elucidates the genetic architecture of shared components of burning mouth syndrome.
Journal of stomatology, oral and maxillofacial surgery - 1 Mar 2026
Lian Qiwu, Dong Linsheng, Zhou Qiaoyu, Yuan Qian
Abstract excerpt
BACKGROUND: Burning mouth syndrome (BMS) is a chronic oral pain condition with unclear etiology. We sought to delineate the shared genetic architecture underlying BMS by modeling a latent BMS factor from multiple related traits. METHODS: We analyzed summary statistics from six published GWASs of BMS-related phenotypes (Sjögren's syndrome, anxiety, depression, fibromyalgia, migraine, and dysphagia) using genomic...
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