Article
ETV1 is a key regulator of enteroendocrine PYY production.
Disease models & mechanisms - 1 Dec 2025
Baattrup Astrid M, Pedersen Marianne Terndrup, Hansen Stine L, Maimets Martti, Gribble Fiona, Reimann Frank, Jensen Kim B
Abstract excerpt
The intestine is a rich source of hormones that regulate metabolism. Among these are glucagon-like peptide-1 (GLP-1) and peptide YY (PYY), both expressed by L-cells. These hormones play important roles in promoting satiety; however, how they are regulated transcriptionally is not known. ETS variant transcription factor 1 (ETV1) is expressed by L-cells, but its function remains unknown. Here, we examined Etv1...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.