Article
ILT-2 and ILT-4 expression and donor genotype as factors associated with HSCT outcome.
Clinical immunology (Orlando, Fla.) - 1 Dec 2025
Siemaszko Jagoda, Łacina Piotr, Szymczak Donata, Szeremet Agnieszka, Majcherek Maciej, Czyż Anna, Sobczyk-Kruszelnicka Małgorzata, Fidyk Wojciech, Solarska Iwona, Nasiłowska-Adamska Barbara, Skowrońska Patrycja, Bieniaszewska Maria, Tomaszewska Agnieszka, Basak Grzegorz W, Giebel Sebastian, Wróbel Tomasz, Bogunia-Kubik Katarzyna
Abstract excerpt
BACKGROUND: NK cell activity after allogeneic haematopoietic stem cell transplantation (HSCT) is still not fully understood. Their cytotoxic activity is modulated by a range of inhibitory and activating surface receptors. Among these, the inhibitory receptors ILT-2 and ILT-4 have yet to be explored in relation to HSCT and its outcomes. METHODS: Genotyping for ILT-2 and ILT-4 was performed using TaqMan assays....
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