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Article

STAT4-associated natural killer cell tolerance following liver transplantation.

Gut - 1 Feb 2017

Jamil K M, Hydes T J, Cheent K S, Cassidy S A, Traherne J A, Jayaraman J, Trowsdale J, Alexander G J, Little A-M, McFarlane H, Heneghan M A, Purbhoo M A, Khakoo S I

Abstract excerpt

OBJECTIVE: Natural killer (NK) cells are important mediators of liver inflammation in chronic liver disease. The aim of this study was to investigate why liver transplants (LTs) are not rejected by NK cells in the absence of human leukocyte antigen (HLA) matching, and to identify a tolerogenic NK cell phenotype. DESIGN: Phenotypic and functional analyses on NK cells from 54 LT recipients were performed, and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26887815
DOI: 10.1136/gutjnl-2015-309395
PMCID: PMC5284485

Genes

STAT4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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