Article
The impact of KIR2DS4 gene on clinical outcome after hematopoietic stem cell transplantation.
Human immunology - 1 Feb 2017
Burek Kamenaric Marija, Stingl Jankovic Katarina, Grubic Zorana, Serventi Seiwerth Ranka, Maskalan Marija, Nemet Damir, Mikulic Mirta, Zunec Renata
Abstract excerpt
Killer cell immunoglobulin-like receptors (KIR) are a family of inhibitory/activating receptors expressed on NK cells. Interactions of KIR receptors with KIR ligands have been shown to modify hematopoietic stem cell transplantation (HSCT) outcome. The aim of this research was to determine the KIR2DS4 allele variants distribution among 111 patients with different hematological malignancy who underwent HSCT and...
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