Article
Novel fibroblast phenotypes in homeostasis and chronic inflammation: From functions to potential regulators.
The Journal of physiology - 1 Jun 2023
Miki Haruka, Manresa Mario C
Abstract excerpt
Fibroblasts are essential components of the stroma, sustaining a variety of tissues and being key to the process of tissue repair after injury. Their role in tissue repair has been attributed to their ability to acquire a contractile, extracellular matrix-producing phenotype known as myofibroblasts. This property is primarily dependent on their response to the pleiotropic cytokine transforming growth factor-β1....
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