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Crosstalk between fibroblasts and immunocytes in fibrosis: From molecular mechanisms to clinical trials

1 Jan 2024

Abstract excerpt

BACKGROUND: The impact of fibroblasts on the immune system provides insight into the function of fibroblasts. In various tissue microenvironments, multiple fibroblast subtypes interact with immunocytes by secreting growth factors, cytokines, and chemokines, leading to wound healing, fibrosis, and escape of cancer immune surveillance. However, the specific mechanisms involved in the fibroblast-immunocyte...

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PMID: 38264932
DOI: 10.1002/ctm2.1545

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