Two-sample Mendelian randomization analysis of 91 circulating inflammatory protein levels and meningioma.

Abstract excerpt

Meningiomas are prevalent central nervous system tumors with unclear etiological mechanisms. Due to their location outside the blood-brain barrier, they may be susceptible to systemic inflammatory responses. This study aimed to explore the causal relationship between 91 inflammatory proteins and meningiomas through 2-sample Mendelian randomization (MR). Using genome-wide association studies data from 14,824...

Topics

• Humans
• Meningioma
• Mendelian Randomization Analysis
• Meningeal Neoplasms
• Polymorphism, Single Nucleotide
• Genome-Wide Association Study