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Article

The role of serum interleukins in Cancer: A Multi-center Mendelian Randomization study.

International immunopharmacology - 20 Aug 2024

Zhang Zheng, Wang Jiachen, Teng Menghao, Yan Xinyang, Liu Qingguang

Abstract excerpt

The occurrence of cancer is often accompanied by immune evasion and tumor-promoting inflammation, with interleukins (IL) playing a pivotal role in the immune-inflammatory mechanism. However, the precise contribution of serum interleukins in cancer remains elusive. We obtained GWAS summary data for 35 interleukins from eight independent large-scale serum proteome studies of European ancestry populations and for 23...

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PMID: 38901247
DOI: 10.1016/j.intimp.2024.112520

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