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Article

Mapping cerebrospinal fluid biomarkers to dementia risk through Mendelian randomization.

Medicine - 26 Sept 2025

Zhu Xiaomin, Chen Wei, Zhuo Guifeng, Yang Chengqing, Fu Yulan, Huang Yingrui, Zhang Ying, Liao Haosen, Wu Lin

Abstract excerpt

Cerebrospinal fluid (CSF) biomarkers can directly reflect physiological and pathological changes within the central nervous system, serving as a critical element in the preliminary diagnosis and disease monitoring of central nervous system disorders. Specific CSF biomarker patterns may be associated with different types of dementia. The goal of this analysis is to scrutinize the causal correlation between 338 CSF...

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Topics

Humans
Mendelian Randomization Analysis
Biomarkers
Dementia
Alzheimer Disease
Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Frontotemporal Dementia

Dementia, Vascular

Source

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Identifiers

PMID: 41029146
DOI: 10.1097/MD.0000000000044658
PMCID: PMC13593241

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