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Article

Proteomic comparison of epidemic Australian Bordetella pertussis biofilm cells.

Microbiology spectrum - 4 Nov 2025

Suyama Hiroki, Luu Laurence Don Wai, Zhong Ling, Raftery Mark J, Lan Ruiting

Abstract excerpt

Bordetella pertussis causes whooping cough, a severe respiratory infectious disease. Studies have compared the currently dominant single nucleotide polymorphism (SNP) cluster I (pertussis toxin promoter allele, ptxP3) and previously dominant SNP cluster II (ptxP1) strains as planktonic cells. Since biofilm formation is linked with B. pertussis pathogenesis in vivo, this study compared the biofilm formation...

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Topics

Bordetella pertussis
Biofilms
Whooping Cough
Bacterial Proteins
Proteomics
Australia
Humans

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Polymorphism, Single Nucleotide

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Identifiers

PMID: 41025661
DOI: 10.1128/spectrum.01715-25
PMCID: PMC12584666

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