Article
Genetically predicted body mass index and maternal outcomes of pregnancy: A two-sample Mendelian randomisation study.
BJOG : an international journal of obstetrics and gynaecology - 1 Mar 2024
Ardissino Maddalena, Geddes-Barton Miranda, Banerjee Anita
Abstract excerpt
OBJECTIVE: Observational studies have described associations between obesity and adverse outcomes of pregnancy but observational results are liable to influence by residual confounding. Mendelian randomisation (MR) leverages the 'natural' genetic randomisation to risk of an exposure occurring at allele assortment and conception. Similar to randomisation in a clinical trial, this limits the potential for the...
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