Childhood obesity and hypertension in pregnancy: a two-sample Mendelian randomization analysis.

Abstract excerpt

BACKGROUND: The causal relationship between childhood obesity and hypertension in pregnancy remains unclear. To examine the causal association between childhood obesity and hypertension in pregnancy, two-sample Mendelian randomization analysis was applied. METHODS: Single-nucleotide polymorphisms (SNPs) associated with childhood obesity were obtained from a published genome-wide association study (GWAS) of 13 848...

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