Article
Childhood obesity and hypertension in pregnancy: a two-sample Mendelian randomization analysis.
Journal of hypertension - 1 Jul 2023
Hu Bing, He Xin, Li Fei, Sun Yanxiang, Sun Jie, Feng Li
Abstract excerpt
BACKGROUND: The causal relationship between childhood obesity and hypertension in pregnancy remains unclear. To examine the causal association between childhood obesity and hypertension in pregnancy, two-sample Mendelian randomization analysis was applied. METHODS: Single-nucleotide polymorphisms (SNPs) associated with childhood obesity were obtained from a published genome-wide association study (GWAS) of 13 848...
Topics
- Child
- Female
- Pregnancy
- Humans
- Genome-Wide Association Study
- Mendelian Randomization Analysis
- Pediatric Obesity
- Hypertension
- Odds Ratio
- Polymorphism, Single Nucleotide