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Article

Obesity and risk of gestational diabetes mellitus: A two-sample Mendelian randomization study.

Diabetes research and clinical practice - 1 Mar 2023

Song Xinli, Wang Cheng, Wang Tingting, Zhang Senmao, Qin Jiabi

Abstract excerpt

AIMS: To estimate genetically predicted causal associations of general and central obesity with GDM, and to determine the mediating role of circulating lipids. METHODS: Summary-level data was obtained from the largest available genome-wide association studies of five obesity traits, five lipid traits and GDM. Two-sample univariate Mendelian randomization (MR), multivariate MR, and MR-based mediation analysis was...

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Identifiers

PMID: 36738839
DOI: 10.1016/j.diabres.2023.110561

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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