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Article

Molecular Characterization of a Rare Glioblastoma Case With Atypical Histopathologic Features.

Oncology (Williston Park, N.Y.) - 15 Sept 2025

Gvazava Nanuli, Tuncer Tolga, Zhang Wei, Kasi Anup, Bhoot Uma

Abstract excerpt

A 76-year-old man presented with a subtle, non-mass-like right insular and temporal opercular T2 FLAIR hyperintensity that remained stable for over 2 years before showing interval progression. Resection revealed mildly hypercellular atypical glial cells with a Ki-67 index of approximately 1% and no necrosis or microvascular proliferation. Immunohistochemistry was negative for IDH1 R132H. Next-generation...

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Identifiers

PMID: 41003641
DOI: 10.46883/2025.25921050

Genes

CDKN2A
EGFR
IDH1
TERT

Variants

Provenance

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