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Article

Proteome-Wide Mendelian Randomisation Study of Adverse Perinatal Outcomes.

Behavior genetics - 1 Sept 2025

Daubney Emily R, Flatley Christopher, Hwang Liang-Dar, Evans David M

Abstract excerpt

Despite significant advances in pre- and postnatal care over the last century, adverse pregnancy related events still occur frequently. We used Mendelian randomisation (MR) to investigate potential causal effects of the mother's and fetal blood proteome on pregnancy related outcomes including birthweight, placental weight, preeclampsia, and sporadic miscarriage. We generated a list of genetic instruments to act...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 40991151
DOI: 10.1007/s10519-025-10233-1
PMCID: PMC12494647

Genes

INHBB
LIMA1
PLCG1
PSG7
SERPINE2
SIGLEC6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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