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Article

Polymorphism of BIK as a Host Risk Factor for Severe Influenza.

DNA and cell biology - 1 Dec 2025

Soni Sourabh, Mebratu Yohannes A

Abstract excerpt

This essay focuses on a key host factor, the protein BIK (Bcl-2-interacting killer), that influences the severity of influenza A virus (IAV) infections. Our recent research published in Proceedings of the National Academy of Sciences describes a novel IAV-BIK-β5 axis that is critical for viral replication. The study demonstrates that BIK is essential for efficient IAV replication, and its overexpression leads to...

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Share to Genetic Predisposition to Disease
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Single Nucleotide

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Identifiers

PMID: 40971288
DOI: 10.1177/10445498251379681
PMCID: PMC13245227

Genes

BIK

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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