Article
Cluster-dependent colistin hetero-resistance in Enterobacter cloacae complex.
The Journal of antimicrobial chemotherapy - 1 Nov 2016
Guérin François, Isnard Christophe, Sinel Clara, Morand Philippe, Dhalluin Anne, Cattoir Vincent, Giard Jean-Christophe
Abstract excerpt
OBJECTIVES: Aims of this study were to: (i) evaluate whether the cluster membership could have an impact on hetero-resistance phenotype to colistin in the Enterobacter cloacae complex (ECC); and (ii) determine the genetic mechanism of colistin hetero-resistance in ECC. METHODS: A collection of 124 clinical isolates belonging to 13 clusters were used to analyse the hetero-resistance phenotype (MICs were determined...
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