Article
Multiclonal Dissemination of ptxP3 Allele Macrolide-Resistant Bordetella pertussis in Okinawa, Japan.
Japanese journal of infectious diseases - 21 May 2026
Kakita Tetsuya, Taira Haruno, Kudeken Tsuyoshi, Kuniyoshi Megumi, Takara Taketoshi, Teruya Morimi, Kyan Hisako, Ohnishi Makoto
Abstract excerpt
An ongoing pertussis epidemic in Okinawa has resulted in 227 reported cases since November 2024. Between December 2024 and February 2025, clinical specimens were collected from 31 cases. We isolated 18 macrolide-resistant Bordetella pertussis (MRBP) strains, all harboring the A2047G mutation in the 23S rRNA gene, confirmed by real-time PCR. Genomic analysis was performed on 2 MRBP strains isolated in November...
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