Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Clinical and genetic features of multiple primary tumours cohorts with a renal cell carcinoma: Implications for molecular genetic investigations.

International journal of cancer - 15 Dec 2025

Zhang Huairen, Yngvadottir Bryndis, Andreou Avgi, Cole Yasemin, Woodward Emma R, Whitworth James, Maher Eamonn R

Abstract excerpt

Multiple primary tumours (MPT) is a risk factor for an underlying predisposition to cancer. Renal cell carcinoma (RCC) occurs in several hereditary cancer disorder syndromes, and RCC-related MPT comprise individuals with multiple primary renal tumours (MPRT) and those with RCC plus a non-renal tumour (MPT:RCC + X). Excluding rare syndromic causes, knowledge of the genetic architecture of MPRT/MPT:RCC + X is...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Aged, 80 and over

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Carcinoma, Renal Cell

Share to Cohort Studies

Share to Exome Sequencing

Share to Germ-Line Mutation

Share to Kidney Neoplasms

Share to Neoplasms, Multiple Primary

Source

Open in PubMed Open full text

Identifiers

PMID: 40844318
DOI: 10.1002/ijc.70085
PMCID: PMC12541567

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 24 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Clinical and genetic features of multiple primary tumours cohorts with a renal cell carcinoma: Implications for molecular genetic investigations.PMID 40844318Read ↗

Germline Susceptibility to Renal Cell Carcinoma and Implications for Genetic Screening.Semantic proximity Read ↗

Hereditary Renal Cancer Syndromes: Clinicopathologic Features and Correlation With Tumors Harboring Somatic Mutations.Semantic proximity Read ↗

Assessment of Genetic Susceptibility to Multiple Primary Cancers through Whole-Exome Sequencing in Two Large Multi-Ancestry StudiesSemantic proximity Read ↗

Genetic Predisposition to Renal Cell Carcinoma: Implications for Counseling, Testing, Screening, and ManagementSemantic proximity Read ↗

Prevalence of Germline Mutations in Cancer Susceptibility Genes in Patients With Advanced Renal Cell Carcinoma.Semantic proximity Read ↗

Assessment of genetic susceptibility to multiple primary cancers through whole-exome sequencing in two large multi-ancestry studies.Semantic proximity Read ↗

Canadian guideline on genetic screening for hereditary renal cell cancersSemantic proximity Read ↗

Renal Cell Cancer Syndromes: Identification and Management of Patients and Families at Increased Risk.Semantic proximity Read ↗

Assessment of Risk of Hereditary Predisposition in Patients With Melanoma and/or Mesothelioma and Renal Neoplasia.Semantic proximity Read ↗

Frequency of pathogenic germline variants in cancer susceptibility genes in 1336 renal cell carcinoma cases.Semantic proximity Read ↗

Referral patterns and genetic testing outcomes in a contemporary hereditary renal cancer clinic.Semantic proximity Read ↗

Outcome of genetic evaluation of patients with kidney cancer referred for suspected hereditary cancer syndromes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.