Genetic Predisposition to Renal Cell Carcinoma: Implications for Counseling, Testing, Screening, and Management

Abstract excerpt

In many individuals with renal cell carcinoma (RCC), a hereditary cause may have contributed to cancer development. Various risk factors can be suggestive of a genetic contribution, including early disease onset, multifocal or bilateral tumors, family history of RCC, and personal/family history of other benign or malignant tumors. Genetic counseling and understanding of the entire family tree are the first steps...

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