Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Assessment of Risk of Hereditary Predisposition in Patients With Melanoma and/or Mesothelioma and Renal Neoplasia.

JAMA network open - 1 Nov 2021

Gupta Sounak, Erickson Lori A, Lohse Christine M, Shen Wei, Pitel Beth A, Knight Shannon M, Halling Kevin C, Herrera-Hernandez Loren, Boorjian Stephen A, Thompson R Houston, Leibovich Bradley C, Jimenez Rafael E, Cheville John C

Abstract excerpt

Importance: In BAP1 tumor predisposition syndrome, clear cell renal cell carcinoma (RCC) is frequently associated with melanoma and/or mesothelioma, while germline MITF p.E318K alterations are being increasingly reported in melanoma/RCC. Limited data exist on the co-occurrence of melanoma and/or mesothelioma with renal neoplasia and the prevalence of associated germline alterations. Objective: To assess the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Germ-Line Mutation
Share to Kidney Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Melanoma

Share to Mesothelioma

Share to Microphthalmia-Associated Transcription Factor

Share to Minnesota

Share to Registries

Share to Ubiquitin Thiolesterase

Source

Open in PubMed Open full text

Identifiers

PMID: 34767027
DOI: 10.1001/jamanetworkopen.2021.32615
PMCID: PMC8590170

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Assessment of Risk of Hereditary Predisposition in Patients With Melanoma and/or Mesothelioma and Renal Neoplasia.PMID 34767027Read ↗

Unveiling the genetic landscape of hereditary melanoma: From susceptibility to surveillance.Semantic proximity Read ↗

Exploring the Link Between Malignant Melanoma and Urological Cancers: A Path Towards Personalized Medicine. Review of the LiteratureSemantic proximity Read ↗

A Systematic Review of Cancer Risks Associated With Mitf VariantsSemantic proximity Read ↗

Germline BAP1 mutations predispose to renal cell carcinomas.Semantic proximity Read ↗

The Importance of Multidisciplinary Approach in Early Detection of BAP1 Tumor Predisposition Syndrome: Clinical Management and Risk AssessmentSemantic proximity Read ↗

Cancer risks associated with the germline MITF(E318K) variant.Semantic proximity Read ↗

Retrospective study of germline variants in patients with hereditary melanoma study criteria in a real clinical practice setting.Semantic proximity Read ↗

Ocular melanoma and the BAP1 hereditary cancer syndrome: implications for the dermatologist.Semantic proximity Read ↗

Identification, genetic testing, and management of hereditary melanoma.Semantic proximity Read ↗

Molecular characterization of melanoma cases in Denmark suspected of genetic predisposition.Semantic proximity Read ↗

BAP1 tumor predisposition syndrome case report: pathological and clinical aspects of BAP1-inactivated melanocytic tumors (BIMTs), including dermoscopy and confocal microscopy.Semantic proximity Read ↗

Combined Genetic and Genealogic Studies Uncover a Large BAP1 Cancer Syndrome Kindred Tracing Back Nine Generations to a Common Ancestor from the 1700s.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.