Article
Anisotropic mechanical properties of pediatric osteogenesis imperfecta bone in three-point bending between disease phenotypes and controls.
Journal of biomechanics - 1 Oct 2025
Radmanovic Katarina, McDonald Maeve, LeSueur Joseph, Canales Bethany, Yang Kai, Smith Peter, Harris Gerald, Fritz Jessica M
Abstract excerpt
Osteogenesis imperfecta (OI) is a relatively common rare bone disease which presents with skeletal deformities and increased fracture incidence. Limited studies have characterized the properties of OI bone, which remains an obstacle in accurately predicting risk of fracture in children with OI during daily activities. To evaluate differences between OI types I, III, IV, VI, VII, and VIII, anisotropic mechanical...
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