Article
Cross-population validation of European GWAS loci for metabolic syndrome in Chinese schizophrenia.
BMC psychiatry - 6 May 2026
You Yangyang, Qiao Ning, Chen Yao, Wang Zhou, Zhuang Lirong, Fang Xinyu, Tang Xiaowei, Zhang Xiangrong
Abstract excerpt
BACKGROUND: Long-term use of second-generation antipsychotics (SGAs) increases the risk of metabolic syndrome (MS) in patients with schizophrenia (SCZ). Using susceptibility loci identified by European Genome-Wide Association Study (GWAS) as entry points, we conducted a case-control study to verify their association with antipsychotic-induced MS in Chinese Han SCZ patients. METHODS: Clinical and metabolic data...
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