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Article

Modeling the genomic architecture of adiposity and anthropometrics across the lifespan.

Nature communications - 13 Aug 2025

Arehart Christopher H, Lin Meng, Gibson Raine A, Raghavan Sridharan, Gignoux Christopher R, Stanislawski Maggie A, Grotzinger Andrew D, Evans Luke M

Abstract excerpt

Obesity-related conditions are among the leading causes of preventable death and are increasing in prevalence worldwide. Body size and composition are complex traits that are challenging to characterize due to environmental and genetic influences, longitudinal variation, heterogeneity between sexes, and differing health risks based on adipose distribution. Here, we construct a 4-factor genomic structural equation...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 40796553
DOI: 10.1038/s41467-025-62730-w
PMCID: PMC12343819

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