IBD-linked Genetic Variance in Intestinal Transplantation: A Multicenter Cohort Analysis.

doi:10.1097/SLA.0000000000006896

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Article

IBD-linked Genetic Variance in Intestinal Transplantation: A Multicenter Cohort Analysis.

Annals of surgery - 1 Nov 2025

Dubois Antoine, Jans Deborah S, Canovai Emilio, Gentilini Maria V, Butler Andrew J, Amin Irum, Sharkey Lisa, Lacaille Florence, Chardot Christophe, Talayero Paloma, Lasa-Lazáro María, Calvo-Pulido Jorge, Wauters Lucas, Vanuytsel Tim, Gondolesi Gabriel E, Pirenne Jacques, Hannes Laurens, Fieuws Steffen, Cleynen Isabelle, Verstockt Sare, Ceulemans Laurens J

Abstract excerpt

BACKGROUND: In solid organ transplantation, the intestine remains the most challenging. Previous studies have linked NOD2 genetic variation to intestinal transplantation (ITx) outcomes. Since then, a larger set of inflammatory bowel disease-associated genetic variants (IBDGVs) has been identified. This study aims to explore the prevalence and association of these IBDGVs with ITx outcomes. METHOD: Clinical data...

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Topics

Humans
Male
Female
Adult
Middle Aged

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Intestines

Graft Survival

Graft Rejection

Inflammatory Bowel Diseases

Nod2 Signaling Adaptor Protein

Genetic Variation

Organ Transplantation

Cohort Studies

Genotype

Adolescent

Source

Open in PubMed

Identifiers

PMID: 40772620
DOI: 10.1097/SLA.0000000000006896

Genes

AR
NOD2

Provenance

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