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Arylsulfatase K attenuates airway epithelial cell senescence in COPD by regulating parkin-mediated mitophagy

31 Jul 2025

Abstract excerpt

Chronic obstructive pulmonary disease (COPD) is a heterogeneous lung condition characterized by irreversible airflow limitation, primarily due to cigarette smoke (CS) exposure. Emerging research underscores the pivotal role of cellular senescence in the pathogenesis of COPD. The arylsulfatase family, known for its involvement in various age-related diseases, has yet to be investigated in the context of COPD. This...

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PMID: 40763656
DOI: 10.1016/j.redox.2025.103793

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